【摘要】 目的探讨住院抑郁症患者服药依从态度及影响因素。方法以2015年7月~2016年7月在深圳市康宁医院临床心理科住院抑郁症患者为研究对象,药物影响因素评定量表(rating of medication influence scale,ROMI)为评定工具,以半结构式访谈评估患者对抗抑郁药物的心态,分析依从态度与患者人口学资料及临床资料的相关性。结果排名前三位的服药原因是遵从专家指示、感到药物对于日常生活的益处、害怕复发,受之影响的患者分别占94.9%、79.8%、75.8%;副作用带来苦恼、对服用的药物或疾病感到尴尬或歧视、现在不需要服药是对患者不服药影响最大的三个因素,受之影响的患者分别占63.6%、38.4%、33.3%;药物知识评分与ROMI依从原因分量表得分呈正相关(t=0.339,P<0.01),与不依从原因分量表得分呈负相关(t=-0.268,P<0.01)。结论药物副作用带来苦恼是不依从的主观原因中值得关注的因素,患者遵从专家指示、感受到药物对日常生活的益处、害怕复发、副作用带来苦恼、对服用的药物或疾病感到尴尬或歧视、患者认为现在不需要服药等因素对药物依从性影响较大,应结合这些因素制定有效的干预措施。更多还原

【Abstract】 Objective To investigate the attitude and influencing factors of medication compliance in patients with depression in hospital. Methods The patients with depression in the clinical psychology department of Shenzhen Kangning Hospital from July 2015 to July 2016 were selected. The ROMI rating of medication influence scale was used as assessment tool. The patient’s mentality in anti-depression medications was evaluated by the semi-structured interviews.The correlation between compliance attitude and patient demographic data, clinical data was analyzed. Results The top three reasons for taking the medicine were following the instructions of the experts, feeling the medicine’s benefit for daily life, fear of recurrence, and the affected patients accounted for 94.9%, 79.8%, and 75.8% respectively. The three most influential factors of patient’s not taking the medicine were distress brought by side effect, feeling embarrassed or discriminated against the drug or disease, no medication needed now, and the affected patients accounted for 63.6%,38.4% and 33.3%,respectively.The drug knowledge score was positively correlated with the ROMI compliance subscale score(t=0.339, P<0.01), and negatively correlated with scores of non-compliance reasons subscale score(t=-0.268, P<0.01). Conclusion Distress caused by drug side effects is a cause worthy of attention in subjective causes of non-compliance. Patients following expert instructions, feeling the medicine’s benefit for daily life, fear of relapse, distress from side effects, feeling embarrassed or discriminated against the drug or disease, and no medication needed now have a greater impact on drug compliance. Effective interventions should be developed combined with these factors.更多还原