【摘要】 目的观察社会认知交互训练(SCIT)对缓解期精神分裂症患者精神症状、社会功能及生活质量的影响。方法 90例精神分裂症患者随机分为干预组和对照组,在原有药物治疗基础上,干预组给予SCIT治疗10周,对照组给予一般心理支持治疗。观察治疗后患者精神症状、社会功能及生活质量的变化。结果干预前两组患者阳性与阴性症状量表(PANSS),社会功能筛选量表(SDSS),家庭功能评定量表(FAD)及生活质量综合评定问卷(GQOLI)评分无明显差异(P>0.05),干预后两组患者PANSS量表阴性症状、阳性症状及PANSS总分均有下降,与干预前相比差异显著(P<0.05),与对照组比较,干预组上述指标改善更明显(P<0.05);干预组SDSS评分和FAD评分较干预前均降低(P<0.05),且低于对照组(P<0.05);干预后,干预组患者躯体功能、生理功能、社会功能及总体生活质量评分较前明显升高(P<0.05),且高于干预后的对照组(P<0.05)。但物质生活满意度评分在干预前后及组间均无明显差异(P>0.05)。结论 SCIT对缓解期精神分裂症患者的社会功能及生活质量具有明显的改善作用,且在一定程度上可缓解精神分裂症患者的临床症状。更多还原

【Abstract】 Objective To investigate the influence of social cognition and interaction training(SCIT) on psychiatric symptoms, social function and life quality of patients with schizophrenia in remission. Methods 90 patients with schizophrenia were randomized into intervention group and control group. Combined with primary medication, patients in intervention group were treated with SCIT for 10 weeks while patients in control group were treated with routine mental supportive treatment. Patients′ psychiatric symptoms, social function and life quality after treatment were observed. Results Scores of positive and negative syndrome scale(PANSS), social disability screening schedule(SDSS),family assessment device(FAD) and general quality of life inventory(GQOLI) in two groups before intervention were not significantly different(P>0.05). Compared with those before intervention, scores of positive syndrome, negative syndrome and total score of PANSS decreased significantly in two groups respectively(P<0.05) and these indicators in intervention group improved more significantly when compared with control group(P<0.05). Scores of SDSS and FAD in intervention group decreased when compare with those before intervention and were lower than those in control group(P<0.05). After intervention, scores of body function, physiological function, social function and quality of life in intervention group increased significantly(P<0.05) and were higher than those in control group after intervention(P<0.05).There were no significant differences of scores of material life satisfaction between before and after intervention or be tween groups( P > 0. 05). Conclusion SCIT could improve the social function and quality of life in patients with schizophrenia in remission significantly and could relieve the clinical symptoms of patients with schizophrenia in remission to some extent.更多还原