Propionibacterium acnes(P. acnes) is human skin commensal bacterium,which plays an important role in the development of acne lesions. We can effectively control and treat acne through inhibiting or killing P. acnes. However,the widespread use of antibiotics led to development of P. acnes resistant to antibiotics. This decreased efficacy of antibiotic treatments for acne,even caused the emergence of other resistant bacterial species,leading to the alteration of human microbial population,what contributes to ...