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柴胡疏肝散治疗老年术后胃肠功能紊乱40例临床研究
Clinical Study on Chaihu Shugan Powder for Treating Elderly Patients with Postoperative Gastrointestinal Dysfunction in 40 Cases
【摘要】 目的观察柴胡疏肝散治疗老年术后胃肠功能紊乱的疗效及对免疫功能的影响。方法选取医院2013月5月至2015年5月收治的老年术后胃肠功能紊乱患者80例,随机分为研究组与对照组,各40例。对照组采用多潘立酮片(吗丁啉)联合马来酸曲美布汀胶囊治疗,研究组采用柴胡疏肝散治疗。结果研究组患者总体疗效显著优于对照组(Z=3.024,P=0.002),总有效率显著高于对照组(97.50%比80.00%,χ2=4.507,P<0.05);治疗后,研究组患者CD3+,CD4+,CD8+,CD4+/CD8+,免疫球蛋白(Ig A,Ig G)补体C3水平均显著高于对照组同期及治疗前(P<0.05);治疗后,研究组Ig M水平显著升高(P<0.05),但与对照组比较无统计学差异(P>0.05)。结论柴胡疏肝散治疗老年术后胃肠功能紊乱疗效显著,同时还可提升免疫功能,值得临床推广。
【Abstract】 Objective To investigate the clinical efficacy of Chaihu Shugan Powder for treating elderly patients with postoperative gastrointestinal dysfunction and its effect on immune function. Methods Totally 80 patients with postoperative gastrointestinal dysfunction admitted to our hospital from May 2013 to May 2015 were selected and randomly divided into the study group and the control group,40 cases in each group. The control group was treated with Domperidone Tablets combined with and Trimebutine Maleate Capsules,while the study group was treated with Chaihu Shugan Powder. Results The overall efficacy of the study group was significantly better than that of the control group( Z = 3. 024,P = 0. 002),and the total effective rate of the study group was significantly higher than that of the control group( 97. 50% vs. 80. 00%,χ2 = 4. 507,P < 0. 05). After treatment,the levels of CD3+,CD4+,CD8+,CD4+/CD8+,immunoglobulin( Ig A and Ig G) complement C3 in the study group were significantly higher than those in the control group and before treatment( P < 0. 05).The level of Ig M in the study group was increased significantly( P < 0. 05),but there was no statistical difference compared with the control group( P > 0. 05). Conclusion Chaihu Shugan Powder in the treatment of elderly patients with postoperative gastrointestinal dysfunction has significant effect,it can improve the immune function,which is worthy of clinical promotion.
【Key words】 Chaihu Shugan Powder; elderly; postoperative; gastrointestinal dysfunction; curative effect; immune function;
- 【文献出处】 中国药业 ,China Pharmaceuticals , 编辑部邮箱 ,2018年08期
- 【分类号】R259
- 【下载频次】56