【摘要】 目的比较慢性阻塞性肺疾病(COPD)评估测试(CAT)与慢性阻塞性肺疾病和支气管哮喘生理评分系统(CAPS)对慢性阻塞性肺疾病急性加重期(AECOPD)患者的病情评估和预测效能。方法采用前瞻性分析的研究方法,选择2014年7月～2017年8月于乌鲁木齐市某三甲医院接受住院治疗的AECOPD患者117例,其中生存105例,死亡12例。对其进行CAT与CAPS评分。采用SPSS及MedC alc统计软件评价相关效能指标,并进行ROC曲线分析。结果 CAT评分灵敏度为88.12%、特异度为75.53%、阳性似然比3.89、阴性似然比0.11、约登指数0.698;CAPS评分的灵敏度为74.32%、特异度为63.57%、阳性似然比2.15、阴性似然比0.31、约登指数0.439;死亡者与生存者的CAT和CAPS评分比较,差异有统计学意义(P <0.05);CAT评分ROC曲线下面积(AUC)为0.648,CAPS评分AUC为0.680,两种评分的AUC比较,差异有统计学意义(P <0.05)。结论相较于CAPS评分,CAT评分可对AECOPD患者实现快速、特异性强及高效能的病情评估,并有着较好的预测价值和指导意义。更多还原

【Abstract】 Objective To compare the disease assessment and prediction efficacy of CAT(chronic obstructive pulmonary disease assessment test) score system and CAPS(the chronic obstructive pulmonary disease and asthma physiology score) system on patients with AECOPD(acute exacerbation of chronic obstructive pulmonary disease). Methods Prospective analysis was adopted, 117 patients with AECOPD from a first-class hospital in Urumqi were received from July 2014 to August 2017 were selected, 105 cases were survived and 12 cases were died. All patients were evaluated by CAT score and CAPS, and statistical SPSS and MedCalc software were used to analyze these evaluation index, and the ROC curve analysis. Results The sensitivity of CAT score was 88.12%, specificity was 75.53%, positive likelihood ratio was 3.89, negative likelihood ratio was 0.11, Youden index was 0.698; the sensitivity of CAPS score was 74.32%,specificity was 63.57%, positive likelihood ratio was 2.15, negative likelihood ratio was 0.31, Youden index was 0.439;there was statistically significant difference in the CAT and CAPS score between death and survival patients(P < 0.05).The area under the curve(AUC) of CAT score was 0.648, the AUC of CAPS score was 0.680, and the comparison of the AUC of two scores was statistically significant(P < 0.05). Conclusion Compared with the CAPS score, CAT score can be used to evaluate the patients with AECOPD in a rapider, more specific and more efficient disease assessment method, which has a good predictive value and guiding significance.更多还原