【摘要】 缺血性脑血管病是常见的慢性致残性疾病,严重影响患者生活质量。研究表明,表皮生长因子受体-细胞外信号调节激酶(EGFR-ERK)通路在缺血性脑血管病的病理生理过程中发挥了重要的作用,但具体机制不详。因此,本文对该通路在缺血性脑血管病中的相关研究进展作一综述,为缺血性脑血管病的进一步基础研究及临床治疗提供参考。更多还原

【Abstract】 Ischemic cerebrovascular disease(ICD) is a common chronic disabling disease. This disease seriously affects the quality of lives of patients. The research shows that the epidermal growth factor receptor-extracellular signal regulated kinase(EGFR-ERK) pathway plays an important role on the pathophysiology process in ICD. However, the mechanism is still unclear. This article reviews the progress of the EGFR-ERK pathway in ICD, which provides references for further basic research and clinical treatment of ICD.更多还原