Angiogenesis is the basic physiological process to maintain the needs of the body. If the angiogenesis is excessive,some diseases can occur. It is well known that the main pathological changes of diabetes is pathological neovascularization,which is affected by a variety of angiogenesis related factors in the body. One of the biological functions of the four factors,Vasohibin,stromal cell-derived factor-1,Ephrin-B2,and Netrin-1,is to regulate the angiogenesis of the body. Recent studies show that the above f...