【摘要】 目的分析老年腔隙性脑梗死(LI)认知功能障碍患者的临床特点。方法选取2014年1月至2016年1月恩施州中心医院收治的104例老年LI患者,根据蒙特利尔认知评估量表(MoCA)评分分为障碍组和无障碍组,比较患者认知功能障碍的发生情况和一般资料。结果 104例患者中有56例发生认知功能障碍(53.85%);障碍组患者的年龄>70岁,体质指数>28 kg/m~2,LI数目,伴有高血压、糖尿病、高血脂、低密度脂蛋白胆固醇>4.16 mmol/L以及有蛋白质病变者高于无障碍组患者(P<0.05)。结论老年LI患者合并认知功能障碍较多见于高龄、肥胖、合并基础疾病、蛋白质病变程度高以及LI数目多的患者。更多还原

【Abstract】 Objective To analyze the clinical characteristics of cognitive dysfunction in elderly patients with lacunar infarction( LI). Methods A total of 104 elderly patients with LI from Jan. 2014 to Jan. 2016 in Enshi Prefecture Central Hospital were selected. According to the Montreal cognitive assessment scale( Mo CA) scores,the patients were divided into a cognitive dysfunction group and a non-cognitive dysfunction group. The incidence of cognitive dysfunction and general data were compared between the two groups. Results Among the 104 LI patients,56 cases( 53. 85%) were with cognitive dysfunction. The patients with age > 70 years old,body mass index > 28 kg/m~2,low density lipoprotein chdesterol >4. 16 mmol/L,multiple LI,with hypertension,diabetes mellitus,hyperlipemia or white matter lesion of the cognitive dysfunction group were more than those of the non-cognitive dysfunction group( P < 0. 05). Conclusion Elderly patients with LI complicated with cognitive dysfunction are more common in the patients featured with elderly,obesity,combined with basic diseases,high degree of protein lesions and higher number of LI.更多还原