【摘要】 目的:探讨超声波治疗恢复期脑梗死的临床效果。方法:选取84例脑梗死恢复期患者,按治疗方法不同分为治疗组(n=40)和对照组(n=44)。对照组给予常规药物及康复治疗,治疗组在对照组基础上加用超声波治疗。采用相关量表评估神经受损、日常活动、肢体运动功能恢复情况,采用超声经颅多普勒血流分析仪评估脑血流动力学情况,并进行疗效与安全性评价。结果:两组治疗前各项量表评分和大脑前动脉、大脑中动脉收缩期最大血流速度(Vs)、平均血流速度(Vm)及阻力指数(RI)比较无统计学意义(P>0.05),治疗后美国国立卫生研究院卒中量表(NIHSS)、改良Barthel指数量表、简式Fugl-Meyer评分量表(FMA)评分均明显改善,Vs、Vm明显升高,RI明显降低,与治疗前相比差异均有统计学意义(P<0.05);与对照组相比,治疗组NIHSS评分显著降低,Barthel指数评分、FMA评分显著增高(P<0.05),且Vs、Vm显著增高,RI显著降低(P<0.05)。治疗组总有效率为87.50%,显著高于对照组的68.18%,差异有统计学意义(P<0.05)。两组治疗期间均未发生明显不良反应。结论:在常规药物康复治疗基础上联合超声波治疗,可明显促进脑梗死患者神经受损、日常活动及肢体运动功能恢复,并增加颅内血管血供,有助于提高临床疗效和改善预后。更多还原

【Abstract】 Objective To investigate the clinical effect of ultrasound waves in the treatment of cerebral infarction at convalescence. Methods Eighty-four patients with cerebral infarction at convalescence were selected and divided into treatment group(n=40) and control group(n=44) according to different treatment methods. The patients in control group were given routine drug rehabilitation therapy, while the patients in treatment group were treated with ultrasound waves and routine drug rehabilitation therapy. The status of nerve injury, daily activities and recovery of limb motor function were evaluated by related scales; the cerebral hemodynamics was assessed with transcranial Doppler blood flow analyzer; and the curative efficacy and safety were also evaluated. Results No significant differences were found between the two groups in scores of different scales, the anterior and middle cerebral artery peak systolic blood flow velocity(Vs), the average blood flow velocity(Vm), and resistance index(RI) before treatment(P>0.05). After treatment, scores of National Institutes of Health Stroke Scale(NIHSS), modified Barthel index and simple Fugl-Meyer Assessment(FMA) were improved significantly; Vsand Vmincreased significantly while RI decreased significantly. Compared with those before treatment, the differences were statistically significant(P<0.05). Compared with those in control group, NIHSS score and RI were significantly lower, while the scores of modified Barthel index and FMA, and the Vsand Vmwere significantly higher in the treatment group(P<0.05). The total effective rate of treatment group was significantly higher than that of control group,with statistical differences(87.50% vs 68.18%, P<0.05). No obvious adverse reactions were observed in the two groups during the treatment. Conclusion Routine drug rehabilitation combined with ultrasound waves can significantly promote the recovery of neurological function, daily activities and limb motor function in patients with cerebral infarction, and increase intracranial blood supply, which is helpful to improve the clinical curative effect and prognosis.更多还原