【摘要】 目的:介绍一例罕见的头状地霉肺炎的治疗方法以及药学服务经验。方法和结果:临床药师参与一例高龄头状地霉肺炎病人的治疗过程。通过查阅文献制定了氟康唑联合氟胞嘧啶的治疗方案,该病人对治疗反应较好,但治疗1个月仍不足以根除病菌,复发后再次合用氟康唑和氟胞嘧啶治疗2个月可彻底治愈。作者保留了菌种,6个月后通过体外联合药敏试验进行了验证。结论:氟胞嘧啶与氟康唑联合治疗头状地霉肺炎方案具有效性、安全性和经济性。体外联合药敏试验亦验证了该方案的有效性。更多还原

【Abstract】 Objective:To introduce the treatment of a patient with rare Geotrichum capitatum pneumonia and pharmaceutical care experience.Methods and Results:Clinical pharmacists were directly involved in the treatment of an old patient with Geotrichum capitatum pneumonia.The treatment regimen by combined medication of fluconazole and flucytosine was developed through consultation of related literature,and the patient responded quite well to the treatment.However,1 month of treatment was not sufficient to eradicate Geotrichum capitatum.After relapse,combined medication of fluconazole and flucytosine for another 2 months could completely cure the disease.The bacteria were retained and drug efficacy was verified through combined drug sensitivity test in vitro,6 months later.Conclusion:Fluconazole combine with flucytosine is an effective,safe and economic treatment method for Geotrichum capitatum pneumonia.更多还原