【摘要】 肿瘤的发病率在逐年增高,且发病机制复杂,变异度高,是影响人类健康和生活质量的重大疾病。抗肿瘤的相关研究也一直是医学研究领域的重点、难点。而随着代谢组学的兴起,肿瘤重编程概念的提出,氨基酸代谢已成为抗肿瘤领域相关研究的重要切入点,用于阐明肿瘤发生机制、发现肿瘤治疗新靶点。对氨基酸代谢和肿瘤、肿瘤营养、肿瘤微环境、肿瘤相关基因、抑癌因子、中药疗法的关系进行综述,为肿瘤临床治疗以及进一步研究提供依据和参考。更多还原

【Abstract】 Objective:Recently,with the development of medical technology,more and more diseases have been successfully compromised.However,the incidence of cancer is increasing year by year with complicated pathogenesis and high variability,which is still a major risk factor affecting humans health and the quality of life.Therefore,tumor related research has always been the focus of medical research,and with the new metabonomics,the concept of tumor reprogramming,amino acid metabolism has been widely used in cancer research,to clarify the mechanism of tumorigenesis and found new targets for the treatment of cancer.This article aims to briefly review the research progress of amino acid metabolism in tumor nutrition metabolism,immune microenvironment,mechanism of occurrence and treatment.更多还原