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光叶子花的化学成分研究

Chemical Constituents from Bougainvillea glabra

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【作者】 张冉刘加祥段金超范彬彬宋启示张玉梅

【Author】 ZHANG Ran;LIU Jiaxiang;DUAN Jinchao;FAN Binbin;SONG Qishi;ZHANG Yumei;Key Laboratory of Tropical Plant Resource and Sustainable Use,Xishuangbanna Tropical Botanical Garden,Chinese Academy of Sciences;University of Chinese Academy of Sciences;Puer University;

【通讯作者】 张玉梅;

【机构】 中国科学院西双版纳热带植物园热带植物资源可持续利用重点实验室中国科学院大学普洱学院

【摘要】 【目的】为进一步开发光叶子花的药用价值,对光叶子花进行了化学成分研究。【方法】通过硅胶、Sephadex LH-20凝胶及RP-C18反相硅胶等色谱柱分离纯化,并运用MS和NMR等波谱学方法鉴定化合物的化学结构。【结果】从光叶子花花的工业甲醇提取物中分离得到6个化合物,分别鉴定为:D-松醇(1)、菠甾醇(2)、3-O-[6′-O-palmitoyl-β-D-glucosyl]-spinasta-7,22-diene (3)、胡萝卜苷(4)、isorhamnetin-3-O-(6′′-O-E-feruloyl)-β-D-galactopyranoside (5)、isorhamnetin-3-O-β-D-glucopyranoside (6)。【结论】光叶子花的化学成分研究较少,本文较深入地对其花的化学成分进行了研究,化合物2、5和6均为首次从该植物中分离得到,在一定程度上丰富了光叶子花的化学成分研究,有利于进一步开发其药用价值。

【Abstract】 [Purpose]The study on the chemical constituents of the flower of Bougainvillea glabra Choisy was to exploit its medicinal value.[Method]Compounds were isolated by column chromatography of silica gel, Sephadex LH-20 and RP-C18, and their structures were identified by spectral methods(MS and NMR).[Result]Six compounds were finally isolated and identified as D-pinitol(1), α-spinaterol(2), 3-O-[6′-O-palmitoyl-β-D-glucosyl]-spinasta-7,22-diene(3), daucosterol(4), isorhamnetin-3-O-(6 ′ ′-O-E-feruloyl)-β-D-galactopyranoside(5), and isorhamnetin-3-O-β-D-glucopyranoside(6), respectively.[Conclusion]There are few reports on the chemical constitents of B. glabra,and we extensively investigated the chemical constituents of its flower. Compounds 2, 5 and 6 were isolated from this species for the first time. To a certain extent, our study enriched the chemical constituents of B. glabra. This work will be conducive to the exploiting of the medicinal value of B. glabra.

【基金】 云南省应用基础研究重点项目(2014FA043);中国科学院个性化药物战略性先导科技专项(XDA12040321);中国科学院战略生物资源服务网络计划活性天然化合物发现、评价与转化项目(Y45J051K01);云南省中青年学术技术带头人后备人才项目(2010CI048)
  • 【文献出处】 云南农业大学学报(自然科学) ,Journal of Yunnan Agricultural University(Natural Science) , 编辑部邮箱 ,2018年06期
  • 【分类号】R284.1
  • 【被引频次】1
  • 【下载频次】162
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