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抑郁症患者失眠严重程度与临床特点相关性研究

Study on The Relationship between The Degree of Insomnia and Clinical Characteristics in Patients with Depression

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【作者】 蔡丽飞温盛霖

【Author】 CAI Li-fei;WEN Sheng-lin;Department of Psychopsychology,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangdong Mental Health Center;Department of Psychopsychology,The Third Affiliated Hospital of Sun Yat-sen University;

【通讯作者】 温盛霖;

【机构】 广东省人民医院广东省医学科学院广东省精神卫生中心精神心理科中山大学附属第三医院精神心理科

【摘要】 目的探讨抑郁症患者失眠严重程度与临床特点的相关性。方法分别统计并分析轻中重度三组失眠的抑郁症患者在性别、年龄、发作次数及病程的分布;用汉密顿抑郁量表-24评价的总分及各因子评分评估病情严重程度,比较轻中重度三组失眠患者之间的病情严重程度的差异。结果抑郁症患者失眠严重程度在不同性别(χ~2=7.30,P<0.05)、发病年龄(χ~2=15.75,P<0.05)以及病情严重程度(W=42.06,P<0.05)的差异有统计学意义。抑郁症患者以轻、中度失眠为主,轻度和中度失眠患者各21例,分别占总人数比例的36.8%,重度失眠患者15例,占总人数比例的26.4%;女性以轻度失眠为主,男性以中度失眠为主;失眠程度越严重,发病年龄越晚,病情越严重;而在不同发作次数(χ~2=3.46,P>0.05)以及不同病程(χ~2=2.58,P>0.05)间差异没有统计学意义。结论抑郁症患者以轻中度失眠为主;女性以轻度失眠为主,男性以中度失眠为主;失眠程度越重、发病年龄越晚、抑郁病情也越严重。

【Abstract】 Objective To investigate the relationship between the degree of insomnia and clinical features in patients with depression. Methods Statistical the distribution of gender,age,number of onset and course of disease in patients with insomnia in mild,moderate and severe groups. The total score and each factor score of HAMD-24 were used to evaluate the severity of the disease and to compare the difference of the severity among the mild,moderate and severe insomnia groups. Results The degree of insomnia in patients with depression was significantly different in sex(χ~2=7.30,P<0.05),age of onset(χ~2=15.75,P<0.05)and severity of illness(W=42.06,P<0.05). Among them,patients with depression mainly suffered from mild and moderate insomnia. There were 21 mild insomniacs and 21 moderate insomniacs,accounting for 36.8%,respectively,while there were 15 severe insomniacs,accounting for 26.4%. Female mainly had mild insomnia,while male had moderate insomnia. The more severe the insomnia degree was,the later the onset age started and the more serious the disease was. But there was no statistical difference between the number of onsets(χ~2=3.46,P>0.05)and the course of disease(χ~2=2.58,P>0.05). Conclusions Patients with depression mainly suffered from mild and moderate insomnia and female mainly had mild insomnia,while male had moderate insomnia. The more severe the insomnia degree was,the later the onset age started and the more serious the disease was.depressiondegree of insomniaclinical characteristics

【基金】 广东省科技计划资助项目(2014A020212530)
  • 【文献出处】 循证医学 ,The Journal of Evidence-Based Medicine , 编辑部邮箱 ,2018年06期
  • 【分类号】R749.4
  • 【被引频次】17
  • 【下载频次】225
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