【摘要】 目的研究全程C反应蛋白(fcCRP)、中性粒细胞百分比(NEU%)、白细胞计数(WBC)在急性结石性胆囊炎(ACC)中的临床应用价值。方法比较ACC患者(病例组)与同期健康者(健康对照组)的fcCRP、WBC、NEU%水平,比较fc CRP、NEU%、WBC诊断ACC的敏感度,比较Murphy氏征阳性与Murphy氏征阴性ACC患者的fcCRP、NEU%、WBC水平。结果病例组与健康对照组的fcCRP、WBC、NEU%比较差异均有统计学意义(P<0.001);fcCRP、NEU%、WBC诊断ACC的敏感度分别为95.7%、42.8%、21.7%,比较差异有统计学意义(P<0.001);Murphy氏征阳性与Murphy氏征阴性ACC患者的fcCRP、WBC、NEU%水平比较差异均有统计学意义(P<0.01)。结论 fcCRP能够及时反映ACC患者的感染及其严重程度,与NEU%及WBC相比,其敏感度更高;对于有明显Murphy氏征的ACC患者,fcCRP指标与体征反应更吻合。临床医生可根据fcCRP指标结果对ACC患者快速地做出感染程度判断并制定最佳的治疗方案。更多还原

【Abstract】 Objective To study the clinical application value of the full course C-reactive protein(fcCRP), neutrophil percentage(NEU%) and white blood cell count(WBC) in acute calculous cholecystitis(ACC). Methods The fcCRP, WBC and NEU% levels of the ACC patients(case group) and healthy people at the same period(healthy control group) were compared. The sensitivity of fcCRP, NEU% and WBC in diagnosis of ACC were compared. The fcCRP, WBC and NEU% levels were compared among the ACC patients with positive or negative Murphy’s sign. Results Statistical difference was found in the fcCRP, WBC and NEU% between the case group and healthy control group(P <0.01). The sensitivity of fcCRP, NEU% and WBC in diagnosis of the ACC were 95.7%, 42.8% and 21.7% respectively,with statistical differences(P <0.01). Statistical difference was found in the fcCRP, WBC and NEU% among the ACC patients with positive or negative Murphy’s sign(P <0.05). Conclusions fcCRP can timely reflect the infection and severity of ACC patients and has higher sensitivity compared to NEU% and WBC. For ACC patients with obvious Murphy’s sign, fcCRP is more consistent with physical signs.Clinicians can quickly judge the degree of infection and make the best treatment plan for ACC patients according to fcCRP results.更多还原