Aim To investigate the effects of 2-methoxyestradiol(2-ME2) on the biological behaviors of 6 T-CEM cells( from human acute T lymphoblastic leukemia cells),such as proliferation and apoptosis,and to explore its underlying mechanism. Methods 6 TCEM cells were cocultured with 2-ME2,and MTT colorimetric assay was used to detect the effects of cell proliferation. The DNA fragment method was employed to examine the effect of apoptosis on 6 T-CEM cells.Western blot was applied to assess the effect of Akt,Prospaspa...
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