Large Hollow nanoparticulate aggregates(LHNAs) based on albumin nanoparticles is a promising technology for developing dry powder inhaler(DPI) with good aerodynamic properties in order to provide a new drug delivery system(DDS) for the treatment of lung disease. Improved understanding of molecular interactions could lead to prepare the DDS rationally. Therefore, this investigation utilized computations and experiments to reveal the mechanisms of budesonide(BUD) interactions with bovine serum albumin(BSA) at...
【基金】
The National Natural Science Foundation of China(Grant No.81202469);
Founder of new drug research fund(Grant No.20130527)
【更新日期】
2018-07-09
【分类号】
R943
【正文快照】
1.Introduction Nowadays,acute exposure to air pollution is associatedwith increased respiratory symptoms,leading to reducedlung function due to rapid industrialization,especiallyin developing country.In 2015,358 million peopleglobally have asthma,up from
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