【摘要】 目的比较西藏拉萨地区城市与农村妇女慢性肝胆疾病患病情况,为做好藏区妇女健康教育和慢性病防治工作提供依据。方法采用分层随机抽样方法于2010年从拉萨1市7县抽取916名年龄≥18岁世居藏族妇女进行慢性肝胆疾病B超检查,肝功能测定以及社会人口学相关问卷调查,并于5年后进行随访。结果西藏拉萨地区藏族妇女慢性肝胆疾病2010年和2015年总患病率分别为24. 34%和23. 21%。2010年各类型肝胆疾病患病率由高到低依次为:胆囊结石10. 04%,脂肪肝7. 75%,胆囊炎6. 22%,肝包虫2. 40%,肝血管瘤1. 42%,肝硬化0. 11%。5年后,胆囊结石和肝包虫的患病率稍有降低分别为:7. 59%和1. 98%,而脂肪肝、胆囊炎和血管瘤的患病率稍有增高分别为:9. 90%、7. 92%和1. 65%,肝硬化患病率不变0. 11%。5年随访中城市妇女胆囊结石,脂肪肝的患病率比农村妇女高,而农村妇女胆囊炎和肝包虫的患病率比城市妇女高(P <0. 05)。结论慢性肝胆疾病的发生与年龄、BMI和饮酒相关。应进一步加强拉萨藏族妇女健康教育与健康促进,提倡健康的饮食习惯和生活方式。更多还原

【Abstract】 Objective To compare the prevalence of chronic hepatobiliary diseases of women living in urban and rural areas in Lhasa( Tibet),and to provide evidence of health education and prevention of chronic disease among Tibetan women. Methods A total of 916 native Tibetan women( ≥ 18 years old) from 1 District and 7 Counties in Lhasa were stratified randomly selected for B-ultrasonic examination,liver function test and questionnaires survey relating to social demography in 2010,and were followed up after 5 years. Results The overall prevalence rates of chronic hepatobiliary diseases in 2010 and 2015 among Tibetan women in Lhasa were 24. 34% and 23. 21%,respectively. In 2010,the prevalence rates of different types of chronic hepatobiliary diseases were: 10. 04% for cholelithiasis,7. 75% for hepatic adipose infiltration,6. 22% for cholecystitis,2. 40% for hepatic echinococcosis,1. 42% for hepatic hemangioma and 0. 11% for cirrhosis. After 5 years,the prevalence rates of cholelithiasis and hepatic echinococcosis decreased to 7. 59% and 1. 98%,respectively. The prevalence of hepatic adipose infiltration,cholecystitis and hepatic hemangioma increased to 9. 90%,7. 92% and 1. 65%,respectively. The prevalence of cirrhosis did not change with 0. 11%. During 5 years followed-up study,the prevalence of cholelithiasis and hepatic adipose infiltration was higher in urban women compared to rural women,while the prevalence of cholecystitis and hepatic echinococcosis was higher in rural women than that in urban women( P < 0. 05). Conclusion Age、BMI and alcohol consumption are related to chronic hepatobiliary diseases. Health education and promotion of Tibetan women in Lhasa including healthy diet and lifestyle should be further strengthened.更多还原