【摘要】 目的分析2007-2016年贵州省黔南州户籍居民软组织肉瘤发病特征及变化趋势,为科学地制定有效的防治决策提供参考依据。方法提取贵州省黔南州肿瘤登记处以人群为基础的癌症发病登记数据库资料中2007-2016年确诊的软组织肉瘤的发病信息进行性别、年龄分析,计算发病率、中标率、世标率、年度变化百分比(APC)等。结果 2007-2016年贵州省黔南州户籍居民软组织肉瘤发病149例(男性82例,女性67例),发病率为4.58/10万,中标率为3.05/10万,世标率为3.49/10万。10年中发病率、中标率、世标率的APC分别为4.73%、3.99%和3.96%。各年龄段发病率有缓慢上升趋势,≥76岁以后有所下降。男性和女性各年龄段软组织肉瘤发病率上升趋势基本一致。病理形态学诊断主要以脂肪肉瘤、纤维肉瘤、恶性纤维组织细胞瘤、恶性神经鞘瘤和上皮样肉瘤为主,分别占17.45%、14.75%、14.09%、13.42%、12.08%。结论贵州省黔南州户籍居民10年来软组织肉瘤发病率有上升趋势,应引起高度重视。更多还原

【Abstract】 Objective To analyze the incidence trends and the characteristics of soft tissue sarcoma( STS) among residents in Qiannan area of Guizhou province from 2007 to 2016,so as to provide the basis for making controlling and preventing measures and strategies. Methods Medical information of the cases diagnosed as STS( ICD: C47&C49) from 2007 to 2016 in Qiannan area of Guizhou province was extracted from the population-based database of Qiannan Cancer Registry. Crude incidence rate,age-standardized incidence rate to Chinese population( ASRC) and world population( ASRW) were calculated. The incidence trends and annual percentage change( APC) during last 10 years were analyzed by using Join Point 3. 4. 3 software. Results A total of 149 cases( 82 males,67 females) were diagnosed as STS during the study period and the STS incidence rate,ASRC incidence rate and ASRW incidence rate were 4. 58 per 105 person-years,3. 05 per 105 person-years and 3. 49 per 105 person-years,respectively. Over the past ten years,the crude APC,ASRC and ASRW incidences were 4. 73%,3. 99% and 3.96% respectively. The incidence rates of all ages had an obvious upward trend except that among people over 76 years old. All ages STS incidence rates among men and women also increased with an almost same trend. Through pathomorphism diagnosis,lipoblastoma was the most common subtype,accounting for 17. 45%,followed by fibrosarcoma( 14. 75%),malignant fibrous histiocytoma( 14. 09%),malignant neurinoma( 13. 42%) and epithelioides sarcoma( 12. 08%). Conclusion The incidence of STS remarkably increased in Qiannan area of Guizhou province during 2007-2016 and more attention should be paid to it.更多还原