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微生物组与动物疫病防控

Microbiome in the study of prevention and control of animal infectious diseases

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【作者】 李求春焦新安

【Author】 LI Qiuchun;JIAO Xin’an;Jiangsu Key Laboratory of Zoonosis,Key Laboratory of Prevention and Control of Biological Hazard Factors (Animal Origin) for Agrifood Safety and Quality,Ministry of Agriculture of China,Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses,Yangzhou University;

【机构】 扬州大学江苏省人兽共患病学重点实验室农业部农产品质量安全生物性危害因子(动物源)控制重点实验室江苏省动物重要疫病与人兽共患病防控协同创新中心

【摘要】 微生物组研究的发展推动了人类不断探索人体微生物群与疾病之间的相关性。然而,微生物组学在动物疫病防控中的研究尚处于起步阶段。本文对动物疫病防控领域中微生物组研究所发挥的6个作用进行了阐述:揭示疾病与菌群的相关性,鉴定新发病原体,确立有益于维持机体健康生长的菌群,筛选疾病防控的新药物和新制剂,开发新疫苗或改进疫苗的使用效果,提出更简单有效的防控措施。

【Abstract】 The development of microbiome has been promoting the study on the relationship between human microbiota and diseases. However,few researches have been performed in the study of prevention and control of animal diseases. In this study,we review and illustrate the roles of microbiome in the following directions: the impact of animal microbiota on diseases; identification of novel pathogens; finding probiotics; research and development for new drugs and biological agents; research and development for new vaccines; new,simple and effective measures.

【基金】 国家自然科学基金( 31730094、31320103907);公益性行业( 农业) 专项( 201403054);江苏优势学科建设工程资助项目( PAPD)
  • 【文献出处】 微生物与感染 ,Journal of Microbes and Infections , 编辑部邮箱 ,2018年02期
  • 【分类号】S851.3
  • 【被引频次】1
  • 【下载频次】166
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