Neisseria meningitidis( Neisseria meningitides,Nm) mainly causes bacterial meningitis and other diseases. NhhA( Neisseria hia homologue) is an outer membrane protein from Nm,the major pathogen of meningococcal disease. Previous studies showed that NhhA had some important functions in host-pathogen interactions,such as participation in the asymptomatic nasopharyngeal colonization of meningococcus,induction of macrophage apoptosis,and immuno-stimulatory functions. The protein is in a surface-exposed mode,whic...