节点文献
氟桂利嗪与尼莫地平治疗偏头痛的临床疗效及不良反应发生率对比分析
Comparison of Clinical Efficacy and Incidence of Adverse Reactions Between Flunarizine and Nimodipine in the Treatment of Migraine
【摘要】 目的探讨氟桂利嗪与尼莫地平治疗偏头痛的临床疗效及不良反应发生率。方法将2016年10月—2017年10月在我院神经内科治疗的100例偏头痛患者随机分为两组,对照组采用氟桂利嗪治疗,观察组采用尼莫地平治疗,比较两组患者的临床疗效、头痛发作情况、不良反应。结果观察组胃肠道反应、头晕、心律失常等不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论氟桂利嗪与尼莫地平治疗偏头痛均有良好疗效,尼莫地平相对更佳,且尼莫地平不良反应发生率较低,临床推荐首选尼莫地平治疗偏头痛。
【Abstract】 Objective To investigate the clinical efficacy of flunarizine and nimodipine in the treatment of migraine and the incidence of adverse reactions.Methods 100 patients with migraine who were treated in department of neurology from October 2016 to October 2017 were randomly divided into two groups.The control group was treated with flunarizine.The observation group was treated with nimodipine.The patient’s clinical efficacy,headache,adverse reactions in the two groups were compared.Results The incidence of gastrointestinal reactions,dizziness,arrhythmia and other adverse reactions in the observation group were significantly lower than those in the control group(P < 0.05).Conclusion Both flunarizine and nimodipine have a good curative effect on migraine,nimodipine is relatively better,and the incidence of nimodipine adverse reaction is lower.Nimodipine is the preferred choice for the treatment of migraine.
【Key words】 migraine; nimodipine; flunarizine; efficacy and adverse reactions;
- 【文献出处】 中国卫生标准管理 ,China Health Standard Management , 编辑部邮箱 ,2018年05期
- 【分类号】R747.2
- 【被引频次】5
- 【下载频次】57