【摘要】 目的分析过敏性紫癜患儿早期肾脏损害的相关因素。方法收集2014年3月至2017年11月山西医科大学第一医院儿科收治过的HSP患儿155例,依据是否出现血尿和/或蛋白尿分为非过敏性紫癜肾炎组(NHSPN组,117例)和过敏性紫癜肾炎组(HSPN组,38例)。对比两组患儿临床资料和入院时实验室指标,采用单因素分析和Logistic回归分析早期肾脏损害的危险因素。结果(1)有33.3%的患儿发生肾脏损害,以不同程度的血尿和/或蛋白尿为主要表现;(2)单因素分析示年龄、TC、TG、IgG、IgA、APTT、D-Dimer于NHSPN组和HSPN组之间存在统计学差异(P<0.05);(3)多因素Logistic回顾分析示年龄、TG、IgA是早期肾脏损害的独立危险因素(P<0.05)。结论年龄、TG、IgA与HSP患儿发生早期肾损害密切相关。更多还原

【Abstract】 Objective To analyze the related factors of early renal damage in children with Henoch Schonlein purpura. Method 155 children with HSP in the Department of Pediatrics of the first hospital of Shanxi Medical University from March 2014 to November 2017 were collected.According to the happening of hematuria and/or albuminuria or not were divided into non allergic purpura nephritis group(group NHSPN, 117 cases) and anaphylactoid purpura nephritis group(group HSPN, 38 cases). Compared the clinical data and admission laboratory indexes between the two groups. Result(1). 33.3% of all the children had renal damage, with different levels of hematuria and/or proteinuria.(2). Single factor analysis showed that age, TC, TG, IgG, IgA, APTT, D-Dimer were statistically different between the NHSPN group and the HSPN group(P<0.05).(3). Logistic retrospective analysis showed that age, TG, and IgA were independent risk factors for early renal damage(P<0.05). Conclusion Age, TG and IgA are closely related to the early renal damage in children with HSP.更多还原