【摘要】 目的研究育龄期妇女多囊卵巢综合征(PCOS)发病的危险因素,为预防和减少多囊卵巢发生,提高育龄妇女健康水平提供科学依据。方法采用病例对照研究方法,调查正常育龄期妇女及育龄期多囊卵巢综合征患者各160例。采用Logistic逐步回归分析发病危险因素。结果母亲和姐妹月经不规律、晚睡、常用塑料餐具和一次性餐具、工作压力大、有糖尿病家族史、初潮年龄晚、超重或肥胖、缺乏体育锻炼均为POCS发生的危险因素。经常参加锻炼可以减低发病风险。病例组与对照组睾酮、雌二醇、黄体生成素、促卵泡生成素、泌乳素含量相差较大,4种激素均是病例组高于对照组,差异有统计学意义(P<0.001)。促卵泡生成素病例组低于对照组,差异有统计学意义(t=7.94,P<0.001)。结论 PCOS危险因素有遗传因素和非遗传因素,改变不良生活方式可以降低发病危险;促卵泡生成素降低,睾酮、雌二醇、黄体生成素、垂体泌乳素升高是多囊卵巢综合征的重要实验室检查特征,可以作为协助诊断手段。更多还原

【Abstract】 Objective: To study the risk factors of polycystic ovary syndrome(PCOS) in women of childbearing age and provide a scientific basis for preventing and reducing the occurrence of polycystic ovary and improving the health of women of childbearing age. Methods: A case-control study was used. 160 other disease patients and 160 patients of polycystic ovary syndrome were enrolled in this study. Logistic regression analysis was carried out on the syndrome risk factor. Results: Survey result display there are statistically significant risk factors are: mothers and sisters irregular menstruation,go to bed too late,commonly used plastic tableware and disposable tableware,work pressure is too large,a family history of diabetes,late menarche age,overweight or obesity,lack of physical exercises. Often participate in exercise,can reduce the risk of disease. Results statistical difference was found between case group and control group which be shown in the contents of five hormones. Follicle stimulating hormone case group is lower than the control group(t = 7. 94,P < 0. 001),testosterone,estradiol,luteinizing hormone,prolactin,four kinds of hormones,are all case group is higher than the control group(P <0. 001). Conclusions: PCOS risk factors include genetic factors and non-genetic factors. Changes in the way of life can reduce the risk of morbidity. Laboratory examination characteristics and can be used as a means of assisting diagnosis that follicle-stimulating hormone is decreased,testosterone,estradiol,luteinizing hormone,pituitary prolactin is increased.更多还原