Objective To investigate the deafness-related gene mutation frequency and the hotspots in patients in Fujian province with non-syndromic hearing loss(NSHL).Methods Peripheral blood samples were obtained from 606 cases hearing loss of patients collected after clinical history inquiry and clinical examination.Their genomic DNA was extracted from peripheral blood by extraction kits to undergo polymerase chain reaction,MALDI-TOF-MS and capillary electrophoresis sequencing were employed to detect the mutations o...