【摘要】 目的:探讨肾癌伴发瘤栓的高危因素。方法:回顾性分析112例术后病理诊断为肾恶性肿瘤伴肾静脉或腔静脉瘤栓患者的临床资料,随机抽取112例肾癌不伴发瘤栓的患者作为对照组。分析评价患者性别、年龄、血压、吸烟史、肿瘤大小、病理类型、Fuhrman分级及血浆纤维蛋白原与瘤栓发生的关系。采用单因素和多因素Logistic回归分析肾癌伴发瘤栓的高危因素。结果:单因素分析结果表明,吸烟史、肿瘤大小、血浆纤维蛋白原、Fuhrman分级与肾癌伴发瘤栓有关(P<0.05)。多因素Logistic回归分析显示,吸烟史、肿瘤大小、血浆纤维蛋白原及Fuhrman分级是肾癌伴发瘤栓的高危因素。结论:有吸烟史或肿瘤体积大或血浆纤维蛋白原升高会增加肾癌患者伴发瘤栓的风险。更多还原

【Abstract】 Objective: To investigate the risk factors for renal carcinoma associated with tumor thrombus. Methods: A retrospective analysis was performed in 112 cases whose postoperative pathological diagnosis was renal malignant tumor with renal vein or vena cava.One hundred and twelve cases of renal cell carcinoma patients associated with tumor thrombus were taken as an observation group, 112 cases of renal cell carcinoma without tumor thrombus were randomly selected as the control group. The relationship between sex, age, blood pressure, smoking history, tumor size, pathological type, Fuhrman grade, and blood fibrinogen with tumor thrombus were analyzed by SPSS.Univariate and multivariate Logistic regression were used to analyze the risk factors for renal cell carcinoma associated with tumor thrombus. Results: The results of univariate analysis showed that smoking history, tumor size, blood fibrinogen and Fuhrman grade were associated with tumor thrombosis(P <0.05). Multivariate logistic regression analysis showed that smoking history, tumor size, blood fibrinogen, and Fuhrman grade were the risk factors for renal cell carcinoma associated with tumor thrombosis. Conclusion: Smoking history, large tumor volume and elevated blood fibrinogen may increase the risk of tumor thrombosis in patients with renal cell carcinoma.更多还原