【摘要】 目的了解北京市本地户籍和流动人口先天性脑积水的流行特征和变化趋势。方法以2006-2012年北京房山、顺义、通州三个区的出生缺陷监测数据为基础,描述脑积水的流行病学特征和产前诊断情况。结果三个区先天性脑积水患病率为4.6/万(89/192811),房山、顺义、通州的患病率分别为5.2/万,5.2/万,4.0/万。流动人口患病率(5.7/万)是本市户籍(3.6/万)的1.6倍(P=0.028)。脑积水产前诊断比例95.5%,孕28周前诊断比例61.4%,其中流动人口孕28周前诊断比例由2006—2008年的35.7%提高至2009—2012年的76.0%。结论2006-2012年北京市三个区先天性脑积水患病率低于全国平均水平,流动人口患病率高于本市人口。流动人口孕28周前诊断比例已达到本市人口水平。应加强对流动人口的先天性脑积水的病因研究。更多还原

【Abstract】 Objective To explore the epidemiological characteristics and time trend of congenital hydrocephalus in Fangshan, Shunyi and Tongzhou districts in Beijing, and to compare the epidemiological characteristics between household and non-household population. Methods Data were obtained from the birth defects surveillance system of three districts of Beijing from 2006 to 2012. The trend of the prevalence of congenital hydrocephalus and prenatal diagnosis was analyzed.Results The prevalence rate of congenital hydrocephalus in the three districts was 4. 6/10000(89/192811), and it’s5.2/10000, 5.2/10000 and 4. 0/10000 respectively in Fangshan, Shunyi and Tongzhou. The prevalence rate of nonhousehold population(5. 7/10000) was 1.6 times higher than that of household population(3. 6/10000). The prenatal diagnosis proportion of congenital hydrocephalus was 95. 5%, and the proportion of the diagnosis before 28 weeks ’gestation was 61. 4%. This proportion in non-household population increased from 35. 7% to 76. 0% in 2006-2012.Conclusion The prevalence of congenital hydrocephalus in these three districts in Beijing was lower than the national average, and the prevalence in non-household population was higher than that in household population. The proportion of the diagnosis before 28 weeks ’ gestation in non-household population increased substantially to the level of the household population in recent years. Further research was needed to strengthen the etiology research of congenital hydrocephalus in non-household population.更多还原