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阿苯达唑脂质体治疗转移性脑泡型包虫病的影像表现

The image findings of albendazole liposome in the treatment of metastatic echinococcosis of the brain

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【作者】 杜小旦姜春晖尤永笑田慧王俭

【Author】 DU Xiaodan;JIANG Chunhui;YOU Yongxiao;TIAN Hui;WANG Jian;Imaging Center,the First Affiliated Hospital of Xinjiang Medical University;

【通讯作者】 王俭;

【机构】 新疆医科大学第一附属医院影像中心

【摘要】 目的 探讨阿苯达唑脂质体治疗脑泡型包虫病(CAE)的CT及MRI变化特点。方法 收集经阿苯达唑脂质体治疗后的符合纳入标准的CAE病例,进行影像学表现回顾性分析。包括经手术病理诊断(5例)和临床诊断(6例)为CAE患者共11例。MRI扫描11例,CT扫描7例,CT、MRI同时扫描4例。结果 11例CAE患者服药前与服药后常规MRI检查中,18.2%(2/11)CAE患者病灶变化不大,81.8%(9/11)CAE患者表现为病灶体积轻度增大,病灶在T2WI上信号升高;7例CAE患者服药前与服药后常规CT检查中,28.5%(2/7)CAE患者病灶变化不大,71.5%(5/7)CAE患者病灶体积轻度增大,钙化范围增大。结论 长期持续的阿苯达唑脂质体治疗CAE期间,病灶体积轻度增大,在T2WI上病灶内信号升高;MRI及CT平扫可以为治疗CAE病变观察提供有价值的影像信息。

【Abstract】 Objective To investigate the imaging features of CT and MRI for albendazole liposome in the treatment of cerebral alveolar echinococcosis(CAE).Methods A retrospective analysis was performed on the CAE after the treatment with albendazole liposomes.11 cases of CAE diagnosed by postoperative pathological diagnosis(5 cases) and clinical diagnosis(6 cases) were collected.MRI scanning were performed in all the patients and CT scanning in 7 cases, CT and MRI were simultaneously scanned in 4 cases. Results On conventional MRI scan of 11 patients with CAE before and after taking medicine, the lesion of 18.2%(2/11) had little change in size, and the size of lesions showed larger in 81.8%(9/11),in which the signal increased on T2WI.On conventional CT examination of 7 cases with CAE before and after taking medicine, 28.5%(2/7) cases had little changes in lesion size, 71.5%(5/7) lesions became larger, and the extent of calcification increased.Conclusion After long-term regular albendazole liposome in the treatment of CAE,the lesion volume increased and the signal is increased on T2WI. MRI and CT scanning can provide valuable imaging information for the treatment of CAE.

【基金】 乌鲁木齐高新技术产业开发区(新市区)科学技术计划项目(Y2012024)
  • 【文献出处】 实用放射学杂志 ,Journal of Practical Radiology , 编辑部邮箱 ,2018年11期
  • 【分类号】R532.32;R816.1;R445.2
  • 【下载频次】1
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