【摘要】 目的 探讨人类免疫缺陷病毒（HIV）继发弓形虫脑炎患者MRI表现,总结其MRI改变特点。方法 回顾性分析本院经临床确诊的35例HIV继发弓形虫脑炎患者MRI图像。结果 35例患者中27例为多发病灶,8例为单发病灶。病变主要累及大脑灰白质交界区或基底节区。MRI表现为片状、结节状或类圆形病灶,T₁WI呈低信号,T₂WI呈略高及不均匀高信号,14例T₂信号内出现不规则液体信号影或结节状稍低信号影,15例出现短T₁信号;18例类圆形病灶可见“牛眼征”;11例增强扫描中单发病变为环形强化;多发病变表现为斑片状、结节状、环形强化共存,部分多发环状强化聚集呈簇状。结论 HIV继发弓形虫脑炎患者的MRI表现为灰白质交界区或基底节区为主多发病变,病变T₁WI出现高信号及T₂WI出现“牛眼征”,增强表现片状、结节状、环形强化病灶同时存在或聚集呈簇状强化,具有一定的特异性。更多还原

【Abstract】 Objective To investigate the MRI manifestations of secondary toxoplasmosis encephalitis in HIV patients and summarize the characteristics of MRI changes.Methods MRI images of 3 5 HIV patients with secondary toxoplasmosis encephalitis were analyzed retrospectively.Results Of 35 patients,27 showed multiple lesions and 8 showed single lesion.Lesions mainly involved the brain gray matter junction or basal ganglia.MRI showed lamellar,nodular or round lesions,which showed low signal on T₁WI,and slightly higher and unevenly high signal on T₂WI.Irregular liquid signal or nodular slightly lower signal was showed on T₂WI in 14 cases,and short T₁ signal was showed in 15 cases.Circular lesions could be seen "cattle eye" in 18 cases.For 11 cases of enhanced scan of a single lesion,a ring enhancement was displayed,and coexistence of patchy,nodular and annular enhancement were showed in multiple lesions,in which parts of the multi-circular enhancemens were clustered.Conclusion MRI manifestations of HIV patients with secondary toxoplasmosis encephalitis show primarily multiple lesions on the gray matter junction or basal ganglia.The lesions show high signal on T₁ WI and "cattle eye" on T₂WI,and existence of flaky,nodular and ring enhanced lesion or clustered enhancement arc showed on enhanced imaging,which is of a certain specificity.更多还原