【摘要】 目的 研究T_1ρ序列对于膝关节骨关节炎（OA）的诊断价值,并对比T_1ρ、MR与关节镜对早期髌骨软骨损伤诊断的敏感性。方法 共扫描28例住院患者的膝关节MRI,经后处理软件处理后,T_1ρ序列轴位测量正常与损伤软骨的T_1ρ值,所有病例均记录MR和关节镜结果。结果 T_1ρ序列可以清晰地显示关节软骨,且呈现不同色阶,正常软骨T_1ρ值均<50 ms,随着软骨损伤的加重T_1ρ值逐渐增高,Ⅰ～Ⅱ级与Ⅲ～Ⅳ级软骨的数值差异有统计学意义。其中9例MR和关节镜下均为0级的软骨在T_1ρ序列上出现T_1ρ值升高,近似于Ⅰ～Ⅱ级软骨损伤,T_1ρ序列对于早期软骨损伤的诊断敏感性高于MR与关节镜。另外,关节镜和MR对于软骨的诊断价值存在较高的一致性。结论 T_1ρ序列能够无创地、有效地预测膝关节OA;T_1ρ序列可先于MR与关节镜发现早期软骨损伤。更多还原

【Abstract】 Objective To explore the value of T_1ρ in the diagnosis of knee osteoarthritis（OA）,and to compare the diagnostic ability of T_1ρ,MR and arthroscopy for early patellar cartilage injury.Methods 28 patients underwent T_1ρ MR imaging.We processed the images and measured Ti p values of the normal and damage cartilage.All cases were recorded results of MR and arthroscopy.Results T_1ρsequence could show cartilage clearly,and performed different colour levels,Tip values of normal cartilage were less than 50 ms,and increased with aggravation of cartilage injury.The differences of Ⅰ-Ⅱ and Ⅲ-Ⅳ had statistically significant.9 cases in grade 0 under MR and arthroscopy performed high values in T_1ρ,which similar to grade Ⅰ-Ⅱ injury,the diagnosis sensitivity of T_1ρ for early cartilage injury was higher than MR and arthroscopy.In addition,arthroscopy and MR had high consistency in the diagnosis of cartilage.Conclusion T_1ρ can effectively predict early cartilage injury and knee OA non-invasively,and can detect early cartilageinjury before MR and arthroscopy.更多还原