Because of damaging the structure and function of organ by infiltrating,and metastasizing,cancer cells seriously affect the health of the body. The advent of atomic force microscopy( AFM) provides a powerful tool for quantifying the mechanical properties of single living cells in aqueous conditions. This paper describes the research progress of cancer cells by atomic force microscopy from four aspects:Mechanical properties of cancer cells,cancer cell extra-cellular matrix,migration of cancer cells,exploring...
【基金】
黑龙江省教育厅科学技术研究项目(编号:12541414)
【更新日期】
2018-06-14
【分类号】
R730.2
【正文快照】
原子力显微镜(atomic force microscopy,AFM)具有纳米和治疗除了肿瘤单细胞的疾病还要考虑到肿瘤微环境的作级分辨率(其成像在哺乳动物细胞上的空间分辨率约为50用,即基质的生物化学和生物物理特性[15]。近年来应用纳米[1]),可以在液体条件下(如细胞培养基)工作,特别适AFM研究?