Objective To investigate the expression of AIB1 protein in endometrial carcinoma and explore its relationship with the expression of Bcl-2 protein. Methods Immunohistochemical SP method was used to detect the expression level of AIB1 and Bcl-2 protein in 15 specimen of normal endometrium tissue and 36 specimen of endometrial carcinoma tissue. The relationship between AIB1 protein expression and clinical features of endometrial carcinoma,and its correlation with the expression of Bcl-2 protein were analyzed....
市肿瘤防治研究重点实验室;3延安大学医学院;*通讯作者,E-mail:qiuxia-pang@sohu.com)乳腺癌扩增1(amplified in breast cancer 1,AIB1)又称为类固醇受体共激活因子3(steroid re-ceptor coactivator-3,SRC-3)是一种雌激素受体共活化物,通过多种信号通路,从而调控细胞的生长、存