【摘要】 目的:探讨实时三维经胸超声心动图检测左心房（LA）功能以评价二尖瓣成形术（MVR）疗效的价值。方法:选择87例二尖瓣关闭不全患者（病例组）分别在MVR术前及术后1 w、24 w采取实时三维经胸超声心动图检测LA的最大容积(maximum volume of LA,LAV_max)、最小容积(the minimum volume of LA,LAV_min)、收缩前容积（systolic volume,LAV_p）及射血分数（ejection fraction,LAEF）、被动射血分数（passive ejection fraction,LAPEF）及主动射血分数（active ejection fraction,LAAEF）等指标,并与同期80例健康志愿者作对照。结果:病例组术前LAV_maxI、LAV_minI、LAV_pI、LAEF、LAPEF、LAAEF值与对照组比较差异有统计学意义（P<0.05）,术后1 w、24 w,LAV_maxI、LAV_minI、LAV_pI、LAEF、LAPEF持续改善（P<0.05）,LAPEF无明显变化（P>0.05）。术后24 w,LA严重扩张由术前58.6%降低到12.6%,67.8%发生LA重构。结论:实时三维经胸超声心动图显示MVR术后LA容积与功能好转,对评价MVR的疗效有一定价值。更多还原

【Abstract】 Objective: To evaluate the clinical value of real-time three-dimensional transthoracic echocardiography for detecting the left atrium（LA） function in mitral valvuloplasty（MVR）. Methods: The maximum volume of LA(LAV_max), minimum volume(LAV_min),systolic volume（LAV_p） and ejection fraction（LAEF）, passive ejection fraction（LAPEF） and active ejection fraction（LAAEF） of 87 cases of patients with mitral regurgitation（case group） were examined by real time three-dimensional transthoracic echocardiography respectively before and at 1 week and 24 weeks after MVR, and compared with 80 healthy volunteers in the same period. Results: The preoperative LAV_maxI, LAV_minI, LAV_pI, LAEF, LAPEF and LAAEF values between the case group and the control group were statistically significant（P<0.05）, the LAV_maxI, LAV_minI, LAV_pI, LAEF and LAPEF values from MVR 1w to 24w were continuously improvement（P<0.05）,while the LAPEF values showed no obvious change（P>0.05）. At 24 weeks postoperation, the proportion of severe LA dilatation decreased from 58.6 % to 12.6 %, and LA remodeling was found 67.8 % cases. Conclusions: Real time three-dimensional transthoracic echocardiography showed LA volume and functional improvement after MVR, which was of some value in evaluating the curative effect of MVR.更多还原