【摘要】 目的:探讨应用多普勒组织运动成像技术(Dopplar Tissue Imaging,DTI)研究二尖瓣环6位点组织运动评估心肌梗死局部及左室整体功能。方法:选取我院心内科及急诊科住院患者,临床上经心肌酶学、心电图、及冠脉造影确诊为心肌梗死患者86例。根据造影结果将其分组:左主干病变7例;前降支病变46例;右冠病变25例;回旋支病变8例;另选取性别、年龄相当的健康志愿者作为对照组。分别进行常规超声心动图检查及二尖瓣环6位点DTI参数测定。将病例组二尖瓣环组织运动速度参数与对照组进行对比分析。结果:1).左主干病变组二尖瓣环3,5位点、1位点DTI参数及6位点DTI参数s波较均值较对照组明显降低(P<0.01);2).前降支病变组和右冠病变组二尖瓣环3,5位点DTI参数s波较对照组明显降低(P<0.01,)1位点及6位点均值DTI参数s波较对照组明显降低(P<0.05);3).回旋支病变组二尖瓣环2,6位点DTI参数s波较对照组明显降低(P<0.05,)1位点及6位点均值DTI参数s波较对照组未见明显降低(P>0.05)4).1位点s波与6位点s波均值与左室EF相关性好,r=0.898和r=0.934.6.左室EF与二尖瓣环1位点s波与心肌梗塞指数呈负相关(r=-0.763)。结论:二尖瓣环6位点组织运动速度可以定量评价心肌梗死局部心肌功能,二尖瓣环位点1与6位点组织运动速度均值相近可定量评价左心室整体功能。更多还原

【Abstract】 Objective: To investigate and study the connectivity between mitral annulus 6 spots tissue motion and myocardial infarction regional & left ventricular whole function by DTI(Dopplar Tissue Imaging). Methods: The 86 inpatients of emergency ward and department of cardiology, they are diagnosed definitely mycardial infarction by myocardial enzyme, electrocardiogram and coronary angiogram. They are divided into groups through coronary angiogram: 7 left main coroary artery, 46 anterior descending branch, 25 right coronary artery artery, 8 circle round branch; The other they healthy volunteers in sexuality and age are looked as control group. We respectively examine in conventional ultrasound and measure detal of mitral annulus 6 sites DTI. The total velocity data in patients is going to contrastive analysis with contral group. Results: 1, In left main coronary artery, the velocity of s wave at mitral annulus 3,5,1 site and main value of 6 sites sites is lower obvious than control group(P<0.01). 2. In anterior descending branch and right coronary artery the velocity of s wave at mitral annulus 3,5 sites is lower obvious than cntrol group(P<0.01); 1 site and main value of 6 sites is lower obvious than control group(P<0.05)3. In circle round branch the velocity of s wave at mitral annulus 2, 6 sites is lower s than control group(P<0.05); 1 site and main value of 6 sites is not lower obvious than control group(P>0.05)4. The connectivity of left ventricular ejective fraction with the velocity of 1 site and main value of 6 sites is obvious, r=0.898 and r=0.934(P <0.01). 5 Left ventricular ejective fraction is inverse correlation with 1 site the velocity of s wave and the number of myocardial infarction, r=-0.763(P<0.01). Conclusion: The velocity of mitral annulus 6 sites quantitive evaluate mycardial infarction regional myocardial function. the velocity of mitral annulus site1 tissue motion, is for the mean of the velocity of mitral annulus 6 sites tissue motion, quantitivly evaluate left ventriculer allomeric function.更多还原