Visceral organs show left-right (L-R) asymmetry with regard to their position and morphology in human. Cilia play an important role in L-R patterning. A number of genes associated with ciliogenesis, motility and Nodal-Pitx2 signal pathway have been identified. The effect of cilia on the asymmetric patterning of or-gans and Nodal-Pitx2 pathway, the relationship between cilia and congenital heart disease, as well as gene identification of L-R asymmetry defects were summarized. These advances will further expa...
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