Whether encoding protein is the golden standard for distinguishing protein coding genes and non-coding RNA(nc RNA), while recent detected peptide coding small open reading frames(s ORFs) from lnc RNA challenged this standard. Now, more and more studies have shown that peptide coding s ORFs exist in different regions of eukaryotic genomes universally, which play important roles in biological activities. Because of the low expression level as well as low abundance and the short sequence length, there are few ...
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