This study focused on the changes of network topological efficiency under the condition of maximizing the intrinsic functional connectivity, and explored the relationships between altered topological efficiency and depressive psychopathology. For this purpose, we collected the resting-state functional MRI data from 20 major depressive disorder(MDD) patients and 20 healthy control(HC) individuals with matching of age, gender and education level. Graph theory analysis showed that the patients with MDD exhibit...
【基金】
supported by grants from The National Basic Research Program of China(2014CB744600);
The National Natural Science Foundation of China(61420106005,61272345);
Open Research Fund of Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics(2014CGZC03);
Beijing Municipal Natural Science Foundation(4164080);
International Science&Technology Cooperation Program of China(2013DFA32180)~~
【更新日期】
2018-02-06
【分类号】
R445.2;R749.4
【正文快照】
Major depressive disorder(MDD)is a mentaldisorder that results from abnormal interactions amongbrain regions engaged in regulating both emotion andcognition[1-2].Recently,the different methodologieshave been used to reveal the neural mechanisms inMDD pati
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