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妊娠及哺乳期女性糖皮质激素和免疫抑制剂的合理应用
Rational application of glucocorticoids and immunosuppressive agents in pregnant or lactating women
【摘要】 妊娠期和哺乳期女性在某些疾病需要服用糖皮质激素和免疫抑制剂时,既要考虑药物的有效作用,还要关注药物对母体、胎儿和待哺婴儿的安全性。哪种糖皮质激素、免疫抑制剂可以在孕期和哺乳期安全应用?哪些药物可以通过胎盘影响胎儿的生长发育、或致畸胎?哪些药物可以通过乳腺分泌入乳汁,作用到新生儿或婴儿?本文将给予较详细的介绍。
【Abstract】 When women during pregnancy and lactation are also complicated with certain diseases,and need to take glucocorticoids and immunosuppressive agents,the doctors should consider not only the efficacy of the drugs,but also the safety of the drugs to the mother,the fetus,and the infant to be fed.Which glucocorticoids and immunosuppressive agents can be safely used during pregnancy and lactation?Which drugs can pass through the placenta to affect the growth and development of the fetus,or to be teratogenic? Which drugs can be secreted into the milk through the breast,acting on newborns or infants?This article gave a more detailed introduction to all of the above topics.
【Key words】 Pregnancy; Lactation; Glucocorticoids; Immunosuppressants;
- 【文献出处】 中华肾病研究电子杂志 ,Chinese Journal of Kidney Disease Investigation(Electronic Edition) , 编辑部邮箱 ,2018年06期
- 【分类号】R714.258
- 【被引频次】13
- 【下载频次】685