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楸叶泡桐种子的苯乙醇苷类化学成分研究

Phenylethanoid Glycosides from Seeds of Paulownia Catalpifolia Gong Tong

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【作者】 薛景王英爱贾献慧杜成林唐文照

【Author】 XUE Jing;WANG Ying-ai;JIA Xian-hui;DU Cheng-lin;TANG Wen-zhao;School of Medicine and Life Sciences, University of Jinan-Shandong Academy of Medical Sciences;Institute of Materia Medica, Key Laboratory for Rare & Uncommon Diseases of Shandong Province, Key Laboratory for Biotech-drugs, Ministry of Health, Shandong Academy of Medical Sciences;

【通讯作者】 唐文照;

【机构】 济南大学山东省医学科学院医学与生命科学学院山东省医学科学院药物研究所国家卫生部生物技术药物重点实验室山东省罕少见病重点实验室

【摘要】 目的研究楸叶泡桐种子的化学成分。方法采用硅胶、Sephadex LH-20、ODS柱色谱等方法对楸叶泡桐种子的70%乙醇提取物进行分离纯化,根据化合物的波谱数据进行结构鉴定。结果从楸叶泡桐种子中分离纯化得到7个苯乙醇苷类化合物,分别鉴定为:ilicifolioside A和isoilicifolioside A混合物(1),isoacteoside(2),plantalloside(3),orobanchoside(4),darendoside B(5),acteoside(6),tomentoside(7)。结论其中,化合物3,4,5为首次从泡桐属中分离得到,化合物1,2,6,7为首次从该植物中分离得到。

【Abstract】 Objective To investigate the chemical constituents from the seeds of Paulownia catalpifolia Gong Tong. Methods The compounds were isolated and purified by silica gel, Sephadex LH-20 and ODS column chromatography. Their structural identification was performed on the basis of the spectral data. Results Seven phenylethanoid glycosides were isolated and their structures were identified as ilicifolioside A and isoilicifolioside A(1), isoacteoside(2), plantalloside(3), orobsnchosid(4), darendoside B(5), acteoside(6), tomentoside(7). Conclusion Compounds 3, 4, 5 were isolated from Paulownia genus for the first time, and compounds 1, 2, 6, 7 were isolated from this plant for the first time.

【基金】 山东省医学科学院医药卫生科技创新工程项目;山东省医学科学院2015年计划项目
  • 【分类号】R284.1
  • 【被引频次】1
  • 【下载频次】128
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