【摘要】 【目的】探讨五味双柏散外敷缓解疼痛在髋关节置换术(THA)后早期快速康复中的临床应用效果。【方法】选择行单侧THA患者64例,随机分为试验组33例和对照组31例。2组患者均于术后当天、第1天、第2天常规给予静脉注射帕瑞昔布钠40 mg,每日2次,后均改为口服塞来昔布胶囊200 mg,每日2次。试验组在此基础上,术后第1天给予伤口下缘外敷五味双柏散,每日2次。所有患者若仍有疼痛则额外给予盐酸曲马多缓释片口服。记录2组患者住院天数、住院期间所用曲马多剂量,以及术后第2天、第4天患者的疼痛视觉模拟评分(VAS)情况。【结果】(1)试验组患者的住院天数少于对照组,盐酸曲马多缓释片用量少于对照组,差异有统计学意义(P<0.01)。(2)术后第2天,2组患者VAS评分比较,差异无统计学意义(P>0.05);术后第4天,2组患者VAS评分均较术后第2天改善(P<0.05或P<0.01),且试验组对VAS评分的改善作用明显优于对照组,差异有统计学意义(P<0.01)。【结论】五味双柏散外敷可以减轻THA术后患者的疼痛不适,减少镇痛药物的应用,缩短住院周期,促进THA术后患者的快速康复。更多还原

【Abstract】 Objective To investigate the clinical effect of external application of Wuwei Shuangbai Powder(WSP)on relieving pain of patients after total hip arthroplasty(THA)for fast-track surgery. Method Sixty-four patientsundergoing unilateral THA were selected,and were randomly divided into experimental group(N = 33)and controlgroup(N = 31). Both groups were injected with parecoxib sodium 40 mg twice a day intravenously right after THAand on postoperative day 1 and 2, and then were given oral use of celecoxib capsules 200 mg twice a day.Additionally,the experimental group was given external application of WSP on the wound margin twice a day onpostoperative day 1,and was given extra oral use of Tramadol Hydrochloride Sustained-release Tablets for thepatients still having the pain. The hospitalization days,tramadol dosage during the hospitalization,and VisualAnalogue Scale(VAS)pain scores on postoperative day 2 and 4 in the two groups were recorded and compared.Results(1)The hospitalization days and tramadol dosage during the hospitalization in the experimental group wereless than those in the control group,the difference being significant(P<0.01).(2)The differences of VAS painscores between the two groups were insignificant on postoperative day 2(P>0.05);but on postoperative day 4,the scores were much improved as compared with those on postoperative day 2(P<0.05 or P<0.01),and the improvement in the experimental group was superior to that in the control group(P<0.01). Conclusion Externalapplication of WSP is effective on relieving the pain of post-THA patients,reducing the total dosage of analgesicdrugs,shortening the hospitalization time and promoting the recovery of patients following THA for fast-track surgery.更多还原