【摘要】 目的探讨广州市放射工作人员淋巴细胞微核异常的发生率及其影响因素。方法采用1∶1配对病例对照研究,将2014年1月1日~12月31日,在某中心进行职业健康检查的1050名放射工作人员中淋巴细胞微核率≥6‰者,共24例作为病例组,按同单位、同性别、年龄相差±5岁进行配对,淋巴细胞微核率正常的放射工作人员,共24例作为对照组。根据《放射工作人员职业健康检查表》收集研究对象的一般基线情况、电离辐射接触情况、混杂因素的接触情况及体检项目指标,使用单因素和多因素条件logistic回归分析方法分析淋巴细胞微核异常的影响因素。结果广州市放射工作人员淋巴细胞微核异常发生率为2.29%,单因素和多因素条件logistic回归有统计学意义的变量为吸烟/被动吸烟情况(OR=3.667)。结论广州市放射工作人员淋巴细胞微核异常情况属正常,其中吸烟/被动吸烟情况是淋巴细胞微核率异常的可能危险因素。更多还原

【Abstract】 Objective To understand and discuss the incidence and influencing factors of the lymphocyte micronucleus abnormality in the radiation workers in Guangzhou. Methods Using 1: 1 matched case-control study. Case group: from January 1,2014 to December 31,2014,the lymphocyte micronucleus rate is greater than or equal to 6‰ in the 1050 radiation workers who took occupational health examinations in a center,with a total of 24 cases. Control group: 24 cases of radiation workers who had been examined at the same center and were in the same work unit,gender,age difference ± 5 years,and lymphocyte micronucleus rate were normal. According to the occupational health examination form for radiation workers to collect the general baseline,the ionizing radiation exposure,the contact of confounding factors and the physical examination project indicators of research object. And single factor and multifactor conditional logistic regression analysis was respectively used to analyze the influencing factors of the abnormal lymphocyte micronucleus rate. Results The incidence of the lymphocyte micronucleus abnormality of radiation workers in Guangzhou was 2. 29 ﹪. Smoking or passive smoking was the only statistically significant variable( OR = 3. 667). Conclusion The abnormal condition of lymphocyte micronucleus of the radiation workers in Guangzhou is normal,Smoking or passive smoking is the possible risk factor for the exceeded lymphocyte micronucleus rate.更多还原