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心肌梗死后心力衰竭患者半乳糖凝集素-3变化的研究

The change of Galectin-3 in patients with heart failure after myocardial infarction

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【作者】 高伟勤王忠

【Author】 GAO Wei-qin;The first affiliated hospital of Jiamusi University;

【机构】 佳木斯大学附属第一医院佳木斯市博康医院

【摘要】 目的研究心肌梗死后发生心力衰竭患者的半乳糖凝集素-3(Galectin-3)的变化,并探讨其临床意义。方法选取本院2016年2—8月间在本院住院并诊断心力衰竭的患者共70例,其中有心肌梗死病史的患者35例,无心肌梗死病史的患者35例。健康对照组35例。结果半乳糖凝集素-3水平在心肌梗死病史组与无心肌梗死病史组之间比较有统计学意义(P<0.05),且半乳糖凝集素-3在心力衰竭组及健康对照组之间比较有统计学意义(P<0.05)。结论心力衰竭患者半乳糖凝集素-3的水平显著高于健康对照组,且心肌梗死后心力衰竭患者半乳糖凝集素-3的水平显著高于无心肌梗死病史的心力衰竭患者。

【Abstract】 Objective To study the changes of Galectin-3 in the patients with heart failure after myocardial infarction,and to explore its clinical significance. Methods A total of 70 cases of heart failure patients diagnosed in our hospital from February 2016 to August 2016 were selected,in which there were 35 cases of patients with myocardial infarction,35 cases of patients with no history of myocardial infarction,and 35 cases of healthy patients were enrolled in the control group. Results The level of Galectin-3 in the myocardial infarction group was statistically different from that in the patients without myocardial infarction history( P < 0.05),and the difference was statistically significant between heart failure group and healthy control group( P< 0.05).Conclusions The level of galectin-3 in patients with heart failure was significantly higher than that in healthy control groups,and the level of Galectin-3 in patients with heart failure after myocardial infarction was significantly higher than that in patients with heart failure who had no history of myocardial infarction.

  • 【文献出处】 齐齐哈尔医学院学报 ,Journal of Qiqihar Medical University , 编辑部邮箱 ,2018年14期
  • 【分类号】R542.22;R541.6
  • 【被引频次】1
  • 【下载频次】46
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