【摘要】 目的探讨氨溴索联合莫西沙星对老年重症社区获得性肺炎患者的疗效及外周血T淋巴细胞亚群的影响。方法选取2015年5月—2017年12月入院治疗老年重症社区获得性肺炎的90例患者作为研究对象,随机分为观察组与对照组两组,每组各45例。观察组给予氨溴索联合莫西沙星治疗,对照组仅给予莫西沙星治疗,持续治疗10天后,观察两组患者的治疗效果及临床指标。结果两组患者的总有效率分别为95.56%和82.22%(P<0.05)。治疗后观察组患者症状消失的时间均短于对照组(P<0.05)。观察组患者的T淋巴细胞亚群比例高于对照组(P<0.05)。结论氨溴索联合莫西沙星治疗老年重症社区获得性肺炎患者,提高了患者治疗的有效率,明显改善了患者的症状,提高患者的免疫力。更多还原

【Abstract】 Objective To explore the efficacy of ambroxol combined with moxifloxacin on elderly patients with severe community acquired pneumonia and its influence on peripheral blood T lymphocyte subsets. Methods 90 cases of elderly patients,those who suffered with severe community acquired pneumonia and admitted in our hospital during May 2015 and December 2017,were enrolled in this study and randomly divided into the observation group and the control group,45 cases in each group. The observation group was treated with ambroxol combined with moxifloxacin. The control group was treated with moxifloxacin only. The treatment effect and clinical indexes of the two groups were observed after 10 days of continuous treatment. Results The total effective rates of the two groups were 95.56% and 82.22% respectively( P< 0.05). After treatment,the time of symptom disappearance in the observation group was shorter than that in the control group( P<0.05). The proportion of T lymphocyte subsets in the observation group was higher than that in the control group( P<0.05).Conclusions Ambroxol combined with moxifloxacin in the treatment of elderly patients with severe community acquired pneumonia can improve the efficiency of the treatment,improve the symptoms of the patients and improve the immunity of the patients.更多还原