【摘要】 目的:分析腹主动脉瘤相关危险因素,探索2型糖尿病对腹主动脉瘤发生发展的作用。方法:回顾性分析中国医科大学附属第一医院血管外科2002年1月—2015年12月收治的腹主动脉瘤患者共601例,统计患者相关信息及化验指标,运用统计学方法分析腹主动脉瘤相关因素。结果:糖尿病组患者动脉瘤横径为(51.48±12.50)mm,非糖尿病组动脉瘤横径为(59.36±19.23)mm,差异有统计学意义(P<0.05)。腹主动脉瘤横径与2型糖尿病(标准化系数β=-0.142)及空腹葡萄糖(标准化系数β=-0.108)负相关(P<0.05)。结论:2型糖尿病是腹主动脉瘤的保护性因素,具体机制需要更加深入地研究。更多还原

【Abstract】 Objective: To research risk factors for AAA(abdominal aortic aneurysm)and explore the effect of type2 DM(diabetes mellitus)acting in the development and progression of AAA.Method: All 601 patients with AAA who received the treatment in the First Hospital of China Medical University were accepted CT angiography(CTA) from January 2002 to December 2015, and traumatic AAA, pseudoaneurysm, Syphilitic AAA were excluded. The information for patients was collected and calculated by statistical method to analyzed the association between type2 DM and AAA.Result: The average transverse diameter was significantly smaller in AAA patients with type2 DM than in normal AAA patients(AAA with DM:(51.48±12.50)mm; normal AAA:(59.36±19.23)mm,P<0.05). The transverse diameter of AAA had a negative association with type2 DM(standardized coefficient β=-0.142) and fasting blood-glucose(standardized coefficient β=-0.108). Conclusion:There was a protective role for diabetes type2 on the development of AAA, and environment with high blood glucose might restrict the expansion of AAA. Further research was required to find the underlying mechanisms for this possible association.更多还原