【摘要】 目的:探讨甲状旁腺癌的影像学表现。方法:回顾性分析经手术病理证实的6例甲状旁腺癌患者超声、^99m Tc-MIBI双时相显像SPECT/CT（或SPECT）、MRI、¹⁸F-FDG PET/CT显像资料,并结合文献对照分析。结果:超声表现:原发病灶平均最大直径为27.7 mm;6例均为低回声,其中4例内部回声不均匀,2例伴有钙化影及液化影;3例边界不清,3例边界尚清;4例病灶边缘及内部见点状及条状血流,2例病灶内见血流丰富。^99mTc-MIBI双时相显像:3例阳性,3例阴性;4例行SPECT/CT检查的患者中分析同机融合CT平扫表现,2例边界不清,2例边界尚清,4例均呈低密度影,其中2例伴有钙化影。1例行颈部软组织MRI检查,表现为甲状腺左叶中上部后缘结节,边界清楚,T₁WI呈稍低信号,T₂WI呈稍高信号,压脂像呈高信号。1例术后行¹⁸F-FDG PET/CT显像示全身多发骨骼¹⁸F-FDG不同程度增高,SUVmax为2.5⁸.8,CT示部分骨骼骨质破坏伴软组织肿块形成。结论:甲状旁腺癌的影像表现具有一定的特点,密度不均匀,内伴有钙化影,边界不清有助于甲状旁腺癌的诊断;MRI能显示病变部位及病灶毗邻关系;¹⁸F-FDG PET/CT显像对肿瘤分期、术后评估及随访有帮助。更多还原

【Abstract】 Objective: To study the imaging manifestations of parathyroid carcinoma. Methods: Ultrasonography,99 mTc-MIBI SPECT/CT(or SPECT), MRI findings and18 F-FDG PET/CT of 6 patients with parathyroid carcinoma confirmed pathologically were analyzed retrospectively, and reviewing relevant literatures. Results: Ultrasonography findings: The average maximum diameter of 6 lesions was 27.7 mm; 6 cases manifested hypoechonic, 2 of which had mirocalcifications; 3 cases showed sharp in grey scale while 3 cases presented blurred nodular margin; 4 cases had a little blood flow while 2 cases with rich blood flow.99 mTc-MIBI SPECT/CT(or SPECT) findings: 3 cases were positive and 3 cases were negative; On CT imaging, 2 cases contained microcalcifications. On MRI, 1 case showed slight low signals on T1 WI and slight hyperintensity signals on T2 WI, and hyperintensity signal on T1-weighted sequence. One case of postoperative18 F-FDG PET/CT found intensely high FDG uptake in multiple bones(range of SUVmax: 2.5~8.8) with osteolytic destruction and soft tissue mass. Conclusion: The imaging findings of parathyroid carcinomas have certain features. Heterogeneous intensity, microcalcifications, blurred nodular marginare helpful for diagnosis of parathyroid carcinoma. MRI can clearly manifest the relationship between adjacent tissues.18 F-FDG PET/CT is contributed to restaging, evaluation of postsurgery and follow-up of parathyroid carcinoma.更多还原