【摘要】 目的:研究分化型甲状腺癌（DTC）患者首次接受大剂量¹³¹I"清甲"治疗后唾液腺功能的变化情况。方法:53例DTC术后患者服用3.7 GBq的¹³¹I行"清甲"治疗,于治疗前1周内及治疗后3月行唾液腺动态显像。结果 :53例DTC患者接受碘治疗后唾液腺摄取功能与治疗前无明显差异（P>0.05）,排泄功能与治疗前对比明显减低（P<0.05）。53例中有14例（26.41%）出现口干症状或口干症状加重,这14例患者的唾液腺摄取功能在治疗前后无明显差异（P>0.05）,排泄功能在治疗后明显减低（P<0.05）。结论:DTC术后首次大剂量¹³¹I"清甲"治疗后3月唾液腺摄取功能正常,排泄功能明显受损。更多还原

【Abstract】 Objective: To study the changes of salivary gland function in patients with differentiated thyroid carcinoma（DTC） who underwent high dose ¹³¹I ablative therapy for the first time. Methods: 53 patients with DTC were treated with3.7 GBq of ¹³¹I. Salivary gland dynamic imaging was performed 1 week before treatment and 3 months after treatment. Results:There was no significant difference in salivary gland uptake between before and after iodine treatment in the 53 patients with DTC（P>0.05）, but the excretory function was significantly lower after treatment than that before（P<0.05）. Of 53 patients, 14 cases（26.41%） were with dry mouth symptoms or aggravated dry mouth symptoms. There was no significant difference in salivary gland uptake function between the 14 patients before and after treatment（P>0.05）, but the excretory function was markedly reduced after treatment（P<0.05）. Conclusion: The salivary gland uptake function was normal 3 months after the first high dose ¹³¹I ablative treatment. But the excretion function was significantly impaired.更多还原