【摘要】 目的观察建瓴汤对老年后循环缺血的脑血管危险因素的影响。方法采用随机数字法将114例老年后循环缺血的患者分别纳入观察组(n=57)与对照组(n=57)。对照组采用标准化基础治疗,观察组在标准化治疗基础上加用建瓴汤治疗,2周为1个疗程,连续服用2个疗程。在干预前、4周后分别检测脑血管危险因素,包括血压(记录收缩压和舒张压);空腹检测胆固醇、低密度脂蛋白、甘油三酯、纤维蛋白原和血糖;采用匹兹堡睡眠质量指数量表(PSQI)进行睡眠质量评估,采用汉密尔顿量表(HAMA)进行焦虑程度评估并进行统计学分析与比较。结果与对照组比较,观察组在药物干预后血压(SBP和DBP)较干预前显著降低(P<0.05),PSQI较干预前明显降低(P<0.01),HAMA较干预前显著降低(P<0.05)。2组其他指标值的差异无统计学意义。结论建瓴汤对老年后循环缺血具有降低血压作用,并改善患者的睡眠质量和焦虑程度。更多还原

【Abstract】 Objective To observe the effect of Jianling Decoction on the risk factors of posterior circulation ischemia in the elderly. Methods 114 elderly with posterior circulation ischemia were randomly divided into 2 groups: observation group and control group, 57 in each; basic treatment was applied to the elderly in both groups while Jianling decoction was added to the elderly in observation group, 2 weeks a course and 2 course in total; before treatment and 4 weeks after treatment, the cerebral vascular risk factors were detected, including blood pressure(systolic pressure, SBP and diastole pressure, DBP), fast cholesterol, low density lipoprotein, triglyceride, fibrinogen, Fasting blood-glucose; the sleep quality and anxiety of the elderly were assessed by Pittsburgh sleep quality index(PSQI) and Hamilton anxiety scale(HAMA) and a comparative analysis was made between the 2 groups. Results Compared with the elderly in control group, the blood pressures(SBP and DBP) of the elderly in observation group dropped down much more after treatment than those before treatment(P<0.05) and the scores of PSQI and HAMA were much lower than those before treatment(P<0.05); no statistical differences in other index were found between the 2 groups. Conclusions Jianling Decoction is effective in reducing the blood pressure of the elderly with posterior circulation ischemia and in improving the sleep quality and anxiety.更多还原