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经阴道超声联合GnRH在腹腔镜子宫肌瘤剔除术中的疗效分析

The Analysis of the Efficacy of GnRH in Laparoscopic Myomectomy

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【作者】 李丹孙金豹李锐宋庆雷何文慧高莹纪江海李晶苏海涛

【Author】 LI Dan;SUN Jinbao;LI Rui;SONG Qinglei;HE Wenhui;GAO Ying;JI Jianghai;LI Jing;SU Haitao;The Affiliated Hospital of Southern Medical University/Cangzhou People’s Hospital;

【通讯作者】 孙金豹;

【机构】 南方医科大学附属医院/沧州市人民医院

【摘要】 目的分析经阴道超声联合促性腺激素释放激素(GnRH)在腹腔镜子宫肌瘤剔除术中的疗效及对患者预后的影响。方法选取我院收治的100例行腹腔镜子宫肌瘤剔除术的患者,随机分为对照组和研究组。对照组采用经阴道超声法,研究组采用经阴道超声联合GnRH治疗。观察两组患者的临床治疗效果、手术情况及术后并发症。结果治疗前两组患者各项指标无明显差异(P>0.05);研究组患者的手术时间、输血例数、术中出血量以及住院时间均明显低于对照组(P<0.05);研究组患者术后24 h肠排气、膀胱、输尿管及直肠损伤、血肿和术后切口感染的发生率均显著低于对照组(P<0.05)。结论经阴道超声联合GnRH对腹腔镜子宫肌瘤剔除术的效果理想,值得临床进一步推广应用。

【Abstract】 Objective To analyze the effects of combined use of gonadotropin releasing hormone(GnRH) and transvaginal ultrasound method on laparoscopic myomectomy and its effects on the prognosis of patients. Methods 100 cases of uterine fibroids patients in our hospital were randomly divided into control group and research group. Patients in control group got laparoscopic myomectomy with the leading of transvaginal ultrasound, and those in research group were added with GnRH therapy on the base of treatment of control group. Observe the clinical curative effect, surgery and postoperative complications. Results Before treatment, the indexes of patients had no significant difference between two groups(P>0.05). The operation time, intraoperative bleeding volume, blood transfusion cases and hospitalization time of the research group were significantly less than those of control group(P<0.05). The incidences of postoperative 24 h intestinal exhaust, injury of bladder, ureter and rectum, infection of incision hematoma and other postoperative complications were significantly lower in the research group than in the control group(P<0.05). Conclusion Transvaginal sonography combined with GnRH for hysteromyomectomy had good curative effects, and it is worthy of further clinical application.

【基金】 国家自然科学基金资助项目(81403237);沧州市科技计划项目(151302056)
  • 【文献出处】 肿瘤药学 ,Anti-tumor Pharmacy , 编辑部邮箱 ,2018年05期
  • 【分类号】R737.33
  • 【被引频次】11
  • 【下载频次】43
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