【摘要】 目的总结利用肠液回输治疗新生儿肠造瘘术后功能性短肠综合征的临床疗效与经验。方法回顾性分析本院自2013年1月至2017年12月行肠液回输治疗的新生儿肠造瘘术后患儿临床资料,分析其一般资料、手术情况、肠液回输情况以及治疗恢复情况。结果共14例新生儿肠造瘘术后患儿接受肠液回输治疗,平均出生胎龄为（33.4±2.8）周,出生体重为（2 129±501）g。近端造口与Treitz韧带之间平均距离为（39.6±10.3）cm,远端造口与回盲部之间平均距离为（45.0±18.1）cm,平均造瘘液量为（65.4±9.2）m L·kg^-1·d^-1,肠液回输治疗平均时间为（29.1±9.2）d,回输期间平均体重增长（26.6±6.4）g/d,肠造瘘术后（47.0±14.6）d关瘘。通过肠液回输,全组患儿静脉营养减少或完全由肠内营养代替,未出现与回输肠液直接相关的并发症。结论肠液回输操作安全可行,可减少肠造瘘术后功能性短肠综合征患儿肠外营养,改善患儿关瘘前营养状态。更多还原

【Abstract】 Objective To summarize the institutional experience of treating functional short bowel syndrome( SBS) with refeeding proximal stoma effluent into distal stoma in neonates with enterostomies. Methods A retrospective chart review was conducted for neonates with stoma effluent refeeding from January 2013 to December 2017. Demographics,medical history,surgical procedures,timing and duration of refeedings were analyzed. Enteral and total parenteral nutritional( TPN) requirements,weigh change and complications were recorded. Results Fourteen neonates( gestational age: 33. 4 ± 2. 8 weeks,birth weight: 2 129 ± 501 g) were identified with nutritional or electrolyte complications before refeeding. The average daily stomal output was 65. 4 ±9. 2 ml/kg/d. Weight gain during refeeding was 26. 6 ± 6. 4 g/d with a duration of refeeding lasting 29. 1 ± 9. 2 days( 2 neonates were refed at home) until reanastomoses at 47. 0 ± 14. 6 days after initial surgery. There were no complications and TPN requirements were diminished or even eliminated. Conclusion This technique is both feasible and safe for lessening the necessity of for TPN and electrolyte supplementation in neonates with enterostomies and SBS prior to reanastomosis.更多还原