【摘要】 目的探讨动脉瘤性蛛网膜下腔出血(aneurysmal subarachnoid hemorrhage,a SAH)患者外周血象与意识障碍的相关性。方法选取2015年1月—12月收治的a SAH 35例,均行血常规检测与格拉斯哥昏迷评分(glasgow coma scale,GCS),若分值≥12分为轻度组,<12分为中重度组。分析不同组别与外周血象的关系,绘制受试者工作特征(receiver operating characteristic,ROC)曲线以评价外周血象鉴别意识障碍严重程度的能力。结果与中重度组比较,轻度组血白细胞、中性粒细胞、血红蛋白减少,差异有统计学意义(P<0.05)。Spearman等级相关性分析显示,血白细胞、中性粒细胞、血红蛋白与GCS评分均呈正相关(r=0.472,P=0.005;r=0.420,P=0.013;r=0.363,P=0.035),且白细胞、中性粒细胞、血红蛋白是a SAH患者意识障碍严重程度的独立预测因子。结论血常规检测对预测a SAH患者意识障碍严重程度具有诊断价值。更多还原

【Abstract】 Objective To investigate the relationship between peripheral hemogram and disturbance of consciousness in patients with aneurysmal subarachnoid hemorrhage( a SAH). Methods Thirty-five patients with a SAH who were admitted to our hospital between January 2015 and December 2015 were enrolled in this study. Routine blood tests were performed and Glasgow Coma Scale( GCS) was used for scoring. The patients were divided into two groups: mild group( ≥12 points) and moderate to severe group( < 12 points). The relationship between different groups and peripheral hemogram were analyzed. The receiver operating characteristic( ROC) curve was drawn to evaluate the ability of peripheral hemogram to identify the severity of disturbance of consciousness. Results Compared with the moderate-severe group,the number of white blood cell( WBC),neutrophils,and hemoglobin were decreased slightly in the mild group,suggesting significant differences( P < 0. 05). Spearman rank correlation analysis revealed that WBC,neutrophils and hemoglobin were positively correlated with GCS score( r = 0. 472,P =0. 005; r = 0. 420,P = 0. 013; r = 0. 363,P = 0. 035),which were also independent predictors of the severity of disturbance of consciousness in a SAH patients. Conclusion Routine blood tests is of diagnostic value in predicting the severity of disturbance of consciousness in a SAH patients.更多还原