【摘要】 目的分析胰腺中段切除术(CP)与胰体尾切除术(DP)在治疗胰腺良性与交界性肿瘤中的临床疗效差异。方法采用回顾性描述性研究方法,收集分析我院39例CP与52例DP的病例。观察病人的基本临床特征与术中情况、术后并发症和随访情况。结果 CP组的手术时间为(220. 96±90. 69)分钟,术后进食时间为(4. 29±1. 05)天; DP组手术时间为(275. 52±88. 78)分钟,术后进食时间为(5. 28±2. 22)天,两组比较差异具有统计学意义(P <0. 05)。胰瘘(B+C)、延迟性胃排空障碍、二次手术和死亡率等严重并发症中,两组比较未出现显著差异(P> 0. 05)。与DP组相比,CP组病人在内、外分泌胰腺功能的保存中占明显优势,差异具有统计学意义(P <0. 05)。结论对于位于胰腺颈体部良性肿瘤和低度恶性肿瘤,CP是一种有效的治疗方法。相较于DP,行CP病人能够更好的从术后胰腺的内、外分泌功能保留中获益。更多还原

【Abstract】 Objective To analyze differences in clinical efficacy of central pancreatectomy( CP)and distal pancreatectomy( DP) in the treatment of benign or borderline tumors of the pancreas. Method A retrospective study was used to analyze 39 cases of central pancreatectomy( CP group) and 52 cases of distal pancreatectomy( DP group). The basic clinical features,intraoperative condition,postoperative complications and follow-up of the patients were observed. Result In the CP group,the operation time[( 220. 96 ± 90. 69) min]and diet start time[( 4. 29 ± 1. 05) d]were significantly longer than DP group[( 275. 52 ± 88. 78) min and( 5. 28 ± 2. 22) d]( P < 0. 05). There was no significant difference in serious complications including clinically significant pancreatic fistula( B + C),delayed gastric emptying,reoperative,and mortality( P > 0. 05). Compared with DP group,CP group patients could benefit from long-term postoperative exocrine and endocrine function( P < 0. 05). Conclusion These findings provide a rationale for CP could as an acceptable and reliable procedure,especially in improving the quality of life of patients.更多还原